CD25− T Cells Generate CD25+Foxp3+ Regulatory T Cells by Peripheral Expansion
نویسندگان
چکیده
منابع مشابه
CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion.
Naturally occurring CD4(+) regulatory T cells are generally identified through their expression of CD25. However, in several experimental systems considerable T(reg) activity has been observed in the CD4(+)CD25(-) fraction. Upon adoptive transfer, the expression of CD25 in donor-derived cells is not stable, with CD4(+)CD25(+) cells appearing in CD4(+)CD25(-) T cell-injected animals and vice ver...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2004
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.173.12.7259